The MezoPen is the most innovative tool for skin rejuvenation  at present. It is the improved version of the well-known and famous dermaroller.  Mesopen and (earlier dermaroller)  are  solution for various skin conditions that clients might seek treatment for. These include wrinkles, fine lines, acne scarring, scars and stretch marks. It can also stimulate wound healing, as well as tighten, lift and rejuvenate skin. This means you can offer a broader range of treatments for your clients.

Injury of dermaroller and mesopen Injury of dermaroller and mesopen

Mesopen is a bit safer and more effective in injuring the skin than traditional skin rollers due to its unique vertical micro needling technology. It has a superior effect on collagen and elastine rejuvenation. Active ingredients are directly supplied to the deeper layers of the skin. Mesopen’s multi-speed and adjustable needle depths allow the needles to pierce the skin’s layers at 90 degrees and increases the effectiveness of treatments by increasing the absorption of products, generating less pain and downtime for the patient. Dermapen can effectively treat hard-to-reach places (e.g. around the eyes, nose, and lips).  Because of the vertical delivery, the needles can easily penetrate scar tissue. It promotes scar-less healing and natural collagen reproduction, similar to fractional laser treatments, IPL, laser resurfacing, and chemical peels, but without the side effects and downtime.

We can expect two parallel effect:

1 Collagen production

The presence of collagen in our skin gives skin elasticity over time, however, the water-binding capacity is decreasing continuously, and consequently develop dehydration of the dermis, wrinkles, and the skin loses its elasticity and firmness.

The mechanism of Mezopen injury is a natural process, which gives the therapy a holistic approach to skin therapy. Four major phases of physiological wound response help in stimulating new healthy tissue growth. First, an inflammatory response (1-3 days), to the initial injury promotes the chemotaxis response and proliferation of fibroblasts. The body’s platelets also respond to initiate a wound matrix. This response is the early phase of cell migration to remove debris and bacteria and stimulate the next proliferative phase. During the second phase (3-5 days), the new fibroblasts,  monocytes, keratinocytes of the first phase continue to proliferate and multiply. New collagen will be laid down and deposited with new tissue formation. Next a fibrotic response (5-20 days), of growth factors are released and fibroblasts release collagen. Finally, the maturation stage of new healthy skin takes place from day 28 to two years after treatment. Collagens mature and stiffen and the matrix of new tissue shows 80% to full tensile strength.

2. Ingredients delivered to the targeted area directly to the problematic cells.

In terms of ingredient transport Mezopen is one of the most innovative technology.  The usage of the device allows the practitioner to deliver sterile highly effective molecules directly to the cells.

Mesopen provides the ability to adapt the depth of the micro needles throughout the treatment reducing any discomfort, and find the cells that really needs a support. With Mesopen we incorporate innovative mesotherapy ingredients that are at the forefront of the most advanced medical-aesthetic treatments, to repair the symptoms and tailored to the clients specific requirements, using cutting edge formulations that include Growth Factors and Biomimetic Peptides. It is possible to restore and improve communication between cells and to mimic actions that are found in young skin to accelerate the natural regeneration process.

Mesopen also  can be used to just open channels into the epidermis to allow product penetration combined with no needle mesotherapy.

MezoPen clinical indications:

  • Acne, treatment of scars and surgical scars
  • Eliminate deep wrinkles
  • Stria (pregnancy, obesity strips)
  • Atrophic scars
  • Dehydration
  • Sagging, flabby skin
  • Wrinkles
  • Open pores
  • Hyperpigmentation
  • Age Spots


  • Active skin infections or inflammations
  • Herpes
  • Mole
  • Chronic skin disease
  • Problems with blood clotting
  • Poor healing ability
  • Malignant lesions
  • Active Acne
  • Eczema
  • Facial redness (rosacea)
  • Psoriasis
  • Severe solar keratosis (Long-term exposure to sunlight emerging, rough to the touch, blurry-edged spots)
  • A prominent mole
  • Susceptibility to keloid formation
  • Pregnancy and lactation
  • Fruit acid peels in the six months prior to treatment
  • Allergy to anesthetic cream (lidocaine sensitivity)
  • Various medications such. roacutan, blood thinning or anti-clotting drugs, and medications while taking aspirin and aspirin-containing
  • Diabetes

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